BDBM183110 US9150546, I-248::US9688643, I-248::US9718790, I-0248

SMILES COC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1

InChI Key InChIKey=UDKRZHKBWBJIRH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 183110   

TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM183110(US9150546, I-248 | US9688643, I-248 | US9718790, I...)
Affinity DataIC50:  420nMpH: 7.5 T: 2°CAssay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM183110(US9150546, I-248 | US9688643, I-248 | US9718790, I...)
Affinity DataIC50:  420nMAssay Description:Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM183110(US9150546, I-248 | US9688643, I-248 | US9718790, I...)
Affinity DataIC50:  420nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM183110(US9150546, I-248 | US9688643, I-248 | US9718790, I...)
Affinity DataIC50:  420nMAssay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...More data for this Ligand-Target Pair
In DepthDetails US Patent