BDBM187166 US9670181, 46 4-((6-ethoxy-2-(ethylamino)quinolin-3-yl)methyl)-1-isopropyl-6,7-dimethoxyisoquinolin-3-ol
SMILES CCNc1nc2ccc(OCC)cc2cc1Cc1c(O)nc(C(C)C)c2cc(OC)c(OC)cc12
InChI Key InChIKey=YSULUHPMOZYEET-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 187166
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Allergan
US Patent
Allergan
US Patent
Affinity DataIC50: 29nMpH: 7.4 T: 2°CAssay Description:The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE® from Perkin Elmer). This c...More data for this Ligand-Target Pair