BDBM19425 N-[2-amino-5-(thiophen-2-yl)phenyl]quinoxaline-6-carboxamide::benzamide-type inhibitor, 21

SMILES Nc1ccc(cc1NC(=O)c1ccc2nccnc2c1)-c1cccs1

InChI Key InChIKey=IHJROTPCROQIGM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 19425   

TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

LigandPNGBDBM19425(N-[2-amino-5-(thiophen-2-yl)phenyl]quinoxaline-6-c...)
Affinity DataIC50:  60nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Methylgene

LigandPNGBDBM19425(N-[2-amino-5-(thiophen-2-yl)phenyl]quinoxaline-6-c...)
Affinity DataIC50: >2.00E+4nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Methylgene

LigandPNGBDBM19425(N-[2-amino-5-(thiophen-2-yl)phenyl]quinoxaline-6-c...)
Affinity DataIC50: >2.00E+4nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Methylgene

LigandPNGBDBM19425(N-[2-amino-5-(thiophen-2-yl)phenyl]quinoxaline-6-c...)
Affinity DataIC50:  200nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed