BDBM19585 (2S)-N-{2-[(4-methoxy-3,5-dimethylphenyl)amino]ethyl}-4-methyl-2-[(3-methylphenyl)formamido]pentanamide::arylaminoethyl amide, 3a

SMILES COc1c(C)cc(NCCNC(=O)[C@H](CC(C)C)NC(=O)c2cccc(C)c2)cc1C

InChI Key InChIKey=YHDGNBGQARWTQO-QFIPXVFZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19585   

TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19585((2S)-N-{2-[(4-methoxy-3,5-dimethylphenyl)amino]eth...)
Affinity DataKi:  20nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19585((2S)-N-{2-[(4-methoxy-3,5-dimethylphenyl)amino]eth...)
Affinity DataKi:  107nM ΔG°:  -9.89kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19585((2S)-N-{2-[(4-methoxy-3,5-dimethylphenyl)amino]eth...)
Affinity DataKi:  125nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed