BDBM19664 (2S)-4-(morpholin-4-yl)-4-oxo-2-phenyl-N-[(1S)-1-phenyl-2-{[4-(trifluoromethoxy)phenyl]amino}ethyl]butanamide::succinamide peptidomimetic, 30

SMILES FC(F)(F)Oc1ccc(NC[C@@H](NC(=O)[C@@H](CC(=O)N2CCOCC2)c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=PSBWTPWDDHNYPT-IZZNHLLZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19664   

TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19664((2S)-4-(morpholin-4-yl)-4-oxo-2-phenyl-N-[(1S)-1-p...)
Affinity DataKi:  261nM ΔG°:  -9.34kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19664((2S)-4-(morpholin-4-yl)-4-oxo-2-phenyl-N-[(1S)-1-p...)
Affinity DataKi:  1.05E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19664((2S)-4-(morpholin-4-yl)-4-oxo-2-phenyl-N-[(1S)-1-p...)
Affinity DataKi:  4.84E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed