BDBM196649 US9212144, 4
SMILES Clc1cccc(CNCCc2ccc(NC(=N)c3cccs3)cc2)c1
InChI Key InChIKey=ZZVGLDBDDYESAB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 196649
Affinity DataIC50: 35nMpH: 7.4Assay Description:To test for enzyme inhibition, the hemoglobin capture assay was used to measure nitric oxide production. The assay was performed at 37° C. in HEPES b...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMpH: 7.4Assay Description:To test for enzyme inhibition, the hemoglobin capture assay was used to measure nitric oxide production. The assay was performed at 37° C. in HEPES b...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration tested against neuronal nitric oxide synthase (nNOS ) from rat cerebellumMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibitory concentration tested against bovine endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMpH: 7.4Assay Description:To test for enzyme inhibition, the hemoglobin capture assay was used to measure nitric oxide production. The assay was performed at 37° C. in HEPES b...More data for this Ligand-Target Pair