BDBM196906 US9212196, Derivative 2

SMILES N[C@@H](CCP(O)(=O)C(O)c1ccc(OCC(O)=O)cc1)C(O)=O

InChI Key InChIKey=BGOFVWMHMQISHB-NKUHCKNESA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 196906   

TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universite Paris Descartes

US Patent
LigandPNGBDBM196906(US9212196, Derivative 2)
Affinity DataEC50:  110nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Universite Paris Descartes

US Patent
LigandPNGBDBM196906(US9212196, Derivative 2)
Affinity DataEC50:  4.20E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Universite Paris Descartes

US Patent
LigandPNGBDBM196906(US9212196, Derivative 2)
Affinity DataEC50:  1.16E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM196906(US9212196, Derivative 2)
Affinity DataEC50:  4.20E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM196906(US9212196, Derivative 2)
Affinity DataEC50:  110nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM196906(US9212196, Derivative 2)
Affinity DataEC50:  2.92E+4nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Universite Paris Descartes

US Patent
LigandPNGBDBM196906(US9212196, Derivative 2)
Affinity DataEC50:  2.92E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In DepthDetails US Patent