BDBM202380 US10081606, Compound I-12::US9238629, I-12::US9765038, Compound I-12
SMILES COc1ccccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1
InChI Key InChIKey=DSRXZMGDJDQWJM-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 202380
Affinity DataIC50: 650nMpH: 7.5 T: 2°CAssay Description:Briefly, 10x stocks of EGFR-WT (PV3872) from Invitrogen and
EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif.,
1.13x ATP (AS001A) and...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: <1nMpH: 7.5 T: 2°CAssay Description:Briefly, 10x stocks of EGFR-WT (PV3872) from Invitrogen and
EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif.,
1.13x ATP (AS001A) and...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-249,301-1210,T790M,L858R](Homo sapiens (Human))
Celgene Car
US Patent
Celgene Car
US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: <1nMpH: 7.5Assay Description:The mechanics of the assay platform are best described by the vendor (Invitrogen, Carlsbad, Calif.) on their web site at the following URL: www.invit...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:The mechanics of the assay platform are best described by the vendor (Invitrogen, Carlsbad, Calif.) on their web site at the following URL: www.invit...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMpH: 7.5Assay Description:The mechanics of the assay platform are best described by the vendor (Invitrogen, Carlsbad, Calif.) on their web site at the following URL: www.invit...More data for this Ligand-Target Pair