BDBM206762 US9260446, (II-S)::US9695185, II-S
SMILES FC(F)(F)c1cccnc1CN1C(=O)[C@@]2(COc3cc4OCCOc4cc23)c2ccccc12
InChI Key InChIKey=XGYVWWLZOMQVRF-QHCPKHFHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 206762
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
US Patent
Xenon Pharmaceuticals
US Patent
Affinity DataIC50: 5nMAssay Description:A radiotracer flux assay used to determine ion flux activity of voltage-gated sodium channels in a high-throughput microplate-based format. The assay...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
US Patent
Xenon Pharmaceuticals
US Patent
Affinity DataIC50: 5nMAssay Description:The assay is based on the guanidine influx assay described by Reddy, N.
L., et al., J. Med. Chem. (1998), 41(17):3298-302. The guanidine influx
ass...More data for this Ligand-Target Pair