BDBM212408 US9290507, II-21

SMILES Cc1ccc(NC(=O)c2ccc(o2)C(C)(C)C)cc1-n1cc(nn1)-c1cncc(c1)N1CCNCC1

InChI Key InChIKey=SEUPGAKGRSBRCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212408   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM212408(US9290507, II-21)
Affinity DataIC50:  1nMpH: 7.5Assay Description:In a dilution series 10 uL/well of test substance solution are placed in a multiwell plate. The dilution series is selected so that generally a range...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent