BDBM213131 US9278960, 8-38::US9278960, 8-39::US9636337, 8-39
SMILES COc1ccc(c(F)c1)-c1cc(nc2cc(ccc12)C(C)Cc1cccnc1N)C(N)=O
InChI Key InChIKey=HRAMGXORLGQLPY-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 213131
TargetGuanine nucleotide-binding protein subunit alpha-15 [Y147C]/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 33nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
TargetGuanine nucleotide-binding protein subunit alpha-15 [Y147C]/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 14nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair