BDBM213233 Telomestatin (TMS)

SMILES [H]C12CSC(=N1)c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1nc(oc1C)-c1nc2oc1C

InChI Key InChIKey=YVSQVYZBDXIXCC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 213233   

TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center

LigandPNGBDBM213233(Telomestatin (TMS))
Affinity DataIC50:  2.20nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center

LigandPNGBDBM213233(Telomestatin (TMS))
Affinity DataIC50:  1.90nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center

LigandPNGBDBM213233(Telomestatin (TMS))
Affinity DataIC50:  1nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center

LigandPNGBDBM213233(Telomestatin (TMS))
Affinity DataIC50:  1.5nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center

LigandPNGBDBM213233(Telomestatin (TMS))
Affinity DataIC50:  2nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed