BDBM21855 2-benzyl-1'-(4-tert-butylcyclohexyl)-5-fluoro-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-3-one::Piperidine Derivative, 5t

SMILES CC(C)(C)C1CCC(CC1)N1CCC2(CC1)C(=O)N(Cc1ccccc1)Cc1cccc(F)c21

InChI Key InChIKey=ULJCQGLYNWZIBP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 21855   

TargetNociceptin receptor(Homo sapiens (Human))
Istituto Superiore Di Sanita

LigandPNGBDBM21855(2-benzyl-1'-(4-tert-butylcyclohexyl)-5-fluoro-2,3-...)
Affinity DataKi:  81nM ΔG°:  -9.57kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Istituto Superiore Di Sanita

LigandPNGBDBM21855(2-benzyl-1'-(4-tert-butylcyclohexyl)-5-fluoro-2,3-...)
Affinity DataKi:  190nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Istituto Superiore Di Sanita

LigandPNGBDBM21855(2-benzyl-1'-(4-tert-butylcyclohexyl)-5-fluoro-2,3-...)
Affinity DataKi:  247nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Istituto Superiore Di Sanita

LigandPNGBDBM21855(2-benzyl-1'-(4-tert-butylcyclohexyl)-5-fluoro-2,3-...)
Affinity DataKi: >1.00E+4nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed