BDBM21894 1-{4-[6-oxo-2-(phenylamino)-6,9-dihydro-3H-purin-9-yl]butyl}-4-phenylpiperidine-4-carbonitrile dihydrochloride::2,9-disubstituted 6-oxopurine, 12r

SMILES O=c1[nH]c(Nc2ccccc2)nc2n(CCCCN3CCC(CC3)(C#N)c3ccccc3)cnc12

InChI Key InChIKey=DJSGKGHDUOHEJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21894   

TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21894(1-{4-[6-oxo-2-(phenylamino)-6,9-dihydro-3H-purin-9...)
Affinity DataIC50:  220nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1)
Glsynthesis

LigandPNGBDBM21894(1-{4-[6-oxo-2-(phenylamino)-6,9-dihydro-3H-purin-9...)
Affinity DataIC50:  410nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed