BDBM221946 US9303035, 1.14
SMILES Cn1c2c3C(NCCn3c(-c3ccccc3)c2c(=O)n(C)c1=O)c1cccc(F)c1F
InChI Key InChIKey=SJKKHHYXVUVADA-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 221946
TargetCystic fibrosis transmembrane conductance regulator(Cricetulus griseus (Chinese hamster))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 11.5nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair