BDBM222148 6,8-dinitro-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-one (4a)

SMILES CC1(C)NC(=O)c2cc(cc(c2N1)[N+]([O-])=O)[N+]([O-])=O

InChI Key InChIKey=MRLQXLJWDPJACL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222148   

TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Sargodha

LigandPNGBDBM222148(6,8-dinitro-2,2-dimethyl-2,3-dihydroquinazolin-4(1...)
Affinity DataIC50:  2.10E+4nMpH: 8.0Assay Description:Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Sargodha

LigandPNGBDBM222148(6,8-dinitro-2,2-dimethyl-2,3-dihydroquinazolin-4(1...)
Affinity DataIC50:  2.44E+4nMpH: 8.0Assay Description:Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed