BDBM222442 3-Chloro-N-[5-(4-chlorobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl]benzo[b]thiophene-2-carboxamide (5f)

SMILES Clc1c(sc2ccccc12)C(=O)NN1C(=S)S\C(=C/c2ccc(Cl)cc2)C1=O

InChI Key InChIKey=FMOBCACWVFDQNN-ZROIWOOFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 222442   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Alexandria University

LigandPNGBDBM222442(3-Chloro-N-[5-(4-chlorobenzylidene)-4-oxo-2-thioxo...)
Affinity DataIC50:  4.90E+3nMAssay Description:All the newly synthesized compounds were screened for their ability to inhibit COX-1 and COX-2 enzymes. This was carried out using Cayman colorimetri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Alexandria University

LigandPNGBDBM222442(3-Chloro-N-[5-(4-chlorobenzylidene)-4-oxo-2-thioxo...)
Affinity DataIC50:  3.74E+3nMAssay Description:All the newly synthesized compounds were also evaluated in vitro for their ability to inhibit lipoxygenase enzyme. This was carried out using Abnova ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Alexandria University

LigandPNGBDBM222442(3-Chloro-N-[5-(4-chlorobenzylidene)-4-oxo-2-thioxo...)
Affinity DataIC50:  1.23E+3nMAssay Description:All the newly synthesized compounds were screened for their ability to inhibit COX-1 and COX-2 enzymes. This was carried out using Cayman colorimetri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed