BDBM22980 2-({2-[(2,6-dichloro-3-methylphenyl)amino]phenyl}formamido)acetic acid::CHEMBL146703::Meclofenamic acid derivative, 32

SMILES Cc1ccc(Cl)c(Nc2ccccc2C(=O)NCC(O)=O)c1Cl

InChI Key InChIKey=QSMQSFSRWWOFAN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22980   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22980(2-({2-[(2,6-dichloro-3-methylphenyl)amino]phenyl}f...)
Affinity DataIC50:  300nMAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM22980(2-({2-[(2,6-dichloro-3-methylphenyl)amino]phenyl}f...)
Affinity DataIC50:  300nMAssay Description:Inhibition of the human Prostaglandin G/H synthase 2 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22980(2-({2-[(2,6-dichloro-3-methylphenyl)amino]phenyl}f...)
Affinity DataIC50:  400nMAssay Description:Inhibition of the ovine Prostaglandin G/H synthase 1 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM22980(2-({2-[(2,6-dichloro-3-methylphenyl)amino]phenyl}f...)
Affinity DataIC50:  400nMAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed