BDBM235555 US9359338, Exe. 165

SMILES CS(=O)(=O)Nc1cc(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)cc(c1)C(F)(F)F

InChI Key InChIKey=OMRQQSCMAHVMJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235555   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Crown Bioscience Inc. (Taiwan)

US Patent
LigandPNGBDBM235555(US9359338, Exe. 165)
Affinity DataIC50:  6.60nMT: 2°CAssay Description:[Experimental method]: Use ADP-GLO™ assay kit from Promega to evaluate the inhibitory activity of compounds at B-Raf. [Instrument]: PerKinElmer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2 [790-1356](Homo sapiens (Human))
Crown Bioscience Inc. (Taiwan)

US Patent
LigandPNGBDBM235555(US9359338, Exe. 165)
Affinity DataIC50:  5.5nMT: 2°CAssay Description:[Experimental method]: Use Lance@Ultra Ulight™-TK assay kit from PerKinElmer to evaluate the inhibitory activity of compounds at KDR kinase. [I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent