BDBM238340 US9394275, I-31

SMILES COc1cc(NC(=O)c2cccc(c2)N(C)C(=O)CCN2CCC(CC2)OC(=O)Nc2ccccc2-c2ccccc2)c(C)cc1CNC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12

InChI Key

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238340   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theravance Respiratory

US Patent
LigandPNGBDBM238340(US9394275, I-31)
Affinity DataKi:  0.200nM ΔG°:  -13.8kcal/moleT: 2°CAssay Description:Displacement assays for determination of Ki values of test compounds were performed with [3H]-NMS at 1 nM and eleven different test compound concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Theravance Respiratory

US Patent
LigandPNGBDBM238340(US9394275, I-31)
Affinity DataEC50:  1nMT: 2°CAssay Description:cAMP assays were performed in a radioimmunoassay format using the Flashplate Adenylyl Cyclase Activation Assay System with [125I]-cAMP (NEN SMP004, P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent