BDBM241116 US9409895, 27::US9630945, 27
SMILES Clc1cc(Cl)cc(COC(=O)N2CCN(CCNC(=O)c3c[nH]c(=O)o3)CC2)c1
InChI Key InChIKey=IKEDPSMWEXUYKV-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 241116
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 375nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 370nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 375nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair