BDBM252426 US9458113, 19.6

SMILES FC(F)(F)c1cccc(c1)N1C2=C(C(NC1=O)c1ccc(cc1-c1cnco1)C#N)C(=O)CC2

InChI Key InChIKey=QMMKGPRXXOVMFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 252426   

TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM252426(US9458113, 19.6)
Affinity DataIC50:  2.40nMpH: 7.5 T: 2°CAssay Description:The following buffers were used: Compound buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5; Assay buffer: 100 mM Tris, 500 mM NaCl, adjusted to p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent