BDBM255506 US9499493, R935237

SMILES COC(=O)Cn1ncc2cc(Nc3ncc(F)c(Nc4cccc(O)c4)n3)ccc12

InChI Key InChIKey=VNLINGUJYFZODD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 255506   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM255506(US9499493, R935237)
Affinity DataIC50:  45.5nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent