BDBM26074 2-benzyl-3-aryl-7-trifluoromethylindazole, 20::3-(4-chlorophenyl)-2-[(2-fluorophenyl)methyl]-7-(trifluoromethyl)-2H-indazole

SMILES Fc1ccccc1Cn1nc2c(cccc2c1-c1ccc(Cl)cc1)C(F)(F)F

InChI Key InChIKey=LMEZNWUTYWBWHN-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26074   

TargetOxysterols receptor LXR-alpha [197-447](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM26074(2-benzyl-3-aryl-7-trifluoromethylindazole, 20 | 3-...)
Affinity DataIC50:  304nM EC50:  1.34E+4nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta [154-461](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM26074(2-benzyl-3-aryl-7-trifluoromethylindazole, 20 | 3-...)
Affinity DataIC50:  38nM EC50:  7.44E+3nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed