BDBM271439 4- (((3aS,5aR,5bR,7aR,9S, 11aR,11bR,13aS)-3a- ((R)-1-hydroxy-2-(4- methylpiperazin-1- yl)ethyl)-1-isopropyl- 5a,5b,8,8,11a- pentamethyl- 3,3a,4,5,5a,5b,6,7,7a,8,9, 10,11,11a,11b,12,13,13a- octadecahydro-2H- cyclopenta[a]chrysen-9- yl)oxy)-2,2-dimethyl-4- oxobutanoic acid::US10064873, Example 65

SMILES [H][C@]12CC[C@]3([H])[C@@]4(C)CC[C@H](OC(=O)CC(C)(C)C(O)=O)C(C)(C)[C@]4([H])CC[C@@]3(C)[C@]1(C)CC[C@]1(CCC(C(C)C)=C21)C(O)CN1CCN(C)CC1

InChI Key InChIKey=BCBFNSSDIKGIOA-OAJQVATFSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 271439   

TargetEnvelope glycoprotein gp160 [V370A](Human immunodeficiency virus 1)
Glaxosmithkline

US Patent
LigandPNGBDBM271439(4- (((3aS,5aR,5bR,7aR,9S, 11aR,11bR,13aS)-3a- ((R)...)
Affinity DataEC50:  3.08E+3nMAssay Description:Antiviral HIV activity and compound-induced cytotoxicity were measured in parallel by means of a propidium iodide based procedure in the human T-cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 (isolate BRU/L...)
Glaxosmithkline

US Patent
LigandPNGBDBM271439(4- (((3aS,5aR,5bR,7aR,9S, 11aR,11bR,13aS)-3a- ((R)...)
Affinity DataEC50:  83.8nMAssay Description:Antiviral HIV activity and compound-induced cytotoxicity were measured in parallel by means of a propidium iodide based procedure in the human T-cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent