BDBM273181 (R)-1-(5-oxo-5H-[1,3,4]thiadiazolo[2,3-b]quinazolin-2-yl)-N-(1-phenylcyclopropyl)pyrrolidine-2-carboxamide::US10065972, Example 655
SMILES O=C(NC1(CC1)c1ccccc1)[C@H]1CCCN1c1nn2c(nc3ccccc3c2=O)s1
InChI Key InChIKey=LXGGDHADSBPRMB-GOSISDBHSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273181
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 29nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair