BDBM275832 5-chloro-4-(3,4- difluorophenoxy)- 2-fluoro-N- sulfamoylbenzamide::US10071957, Example 50

SMILES NS(=O)(=O)NC(=O)c1cc(Cl)c(Oc2ccc(F)c(F)c2)cc1F

InChI Key InChIKey=UIWGCCRSVHAJPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275832   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM275832(5-chloro-4-(3,4- difluorophenoxy)- 2-fluoro-N- sul...)
Affinity DataIC50:  656nMpH: 7.4 T: 2°CAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent