BDBM27706 8-chloro-2-[3-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)propyl]-3,4-dihydroquinazolin-4-one::CHEMBL251029::quinazolinone analogue, 1b
SMILES Clc1cccc2c1nc(CCCN1CCC(=CC1)c1ccccc1)[nH]c2=O
InChI Key InChIKey=RTHFDNGPDMXTQU-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 27706
Affinity DataIC50: 23nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataIC50: 610nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair