BDBM277161 (S) or (R)-4-[1- (difluoromethyl)-1H- pyrazol-4-yl]-7-{(1R)-1-[2- (trifluoromethyl)pyridin-4- yl]ethyl}-5,6,7,8- tetrahydro-1,7- naphthyridine-2- carboxamide::US10072003, Example 7-3A::US10072003, Example 7-3B
SMILES CC(N1CCc2c(C1)nc(cc2-c1cnn(c1)C(F)F)C(N)=O)c1ccnc(c1)C(F)(F)F
InChI Key InChIKey=YDSFBDJOIPTAED-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 277161
Affinity DataIC50: 2.12E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Affinity DataIC50: 2.93E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair