BDBM278457 US10040788, Example 34(a)::US10294221, Example 34(a)

SMILES CCO[C@@H](C(=O)Nc1nnc(N[C@@H]2CCN(C2)c2nccnn2)s1)c1ccccc1

InChI Key InChIKey=ABNHGKDFYFODKC-HUUCEWRRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 278457   

TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM278457(US10040788, Example 34(a) | US10294221, Example 34...)
Affinity DataIC50:  88.1nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM278457(US10040788, Example 34(a) | US10294221, Example 34...)
Affinity DataIC50:  88.1nMpH: 7.8Assay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent