BDBM281114 US10022354, Example 54

SMILES CC(C)c1cc([nH]n1)C(=O)N1CCC(C1)c1cc(NC(C)=O)cc(C)n1

InChI Key InChIKey=ILWPUMUQJZDDAZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 281114   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM281114(US10022354, Example 54)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged KDM5A expressed in baculovirus infected Sf9 insect cells using H3K4me3 peptide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM281114(US10022354, Example 54)
Affinity DataIC50:  1.70nMpH: 7.0 T: 2°CAssay Description:Full length KDM5A enzyme was expressed and purified inhouse. Biotin-H3K4me3 peptide was purchased from New England Biolabs. HTRF reagents (containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent