BDBM285440 4-(2-ethyl-5-methylsulfonyl-2,3-dihydro-1- benzofuran-7-yl)-2-methylisoquinolin-1-one::BDBM486284::US10023592, Example 494
SMILES CCC1Cc2cc(cc(c2O1)-c1cn(C)c(=O)c2ccccc12)S(C)(=O)=O
InChI Key InChIKey=APBFHIMAMCLYHY-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 285440
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair