BDBM28977 2-[({4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl}methane)sulfonyl]pyridine::cyclohexyl sulfone-based compound, 21

SMILES Fc1ccc(F)c(c1)[C@]1(CC[C@H](CS(=O)(=O)c2ccccn2)CC1)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=BNRCMKYOGYXWND-SMQSCJQKSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28977   

LigandPNGBDBM28977(2-[({4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoro...)
Affinity DataEC50:  2.10nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
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