BDBM291370 4-[1-(4-Chlorophenyl)-2-(2- methoxypyridin-4-yl)-1H- pyrrolo[2,3-c]pyridin-3- yl]piperidine-1-carboxamide; formic acid::US9580415, Example 4

SMILES COc1cc(ccn1)-c1c(C2CCN(CC2)C(N)=O)c2ccncc2n1-c1ccc(Cl)cc1

InChI Key InChIKey=FPBZXJSGQZWMOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 291370   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291370(4-[1-(4-Chlorophenyl)-2-(2- methoxypyridin-4-yl)-1...)
Affinity DataIC50:  550nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291370(4-[1-(4-Chlorophenyl)-2-(2- methoxypyridin-4-yl)-1...)
Affinity DataIC50: <100nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent