BDBM292089 4-[4-(1,2,3,3a,4,6,7,7a- octahydropyrrolo[3,2-c]pyridin-5-yl)-1-(4- cyclopropylphenyl)-6-oxopyrimidin-2-yl]- 2-fluorobenzonitrile::US10100046, Example 27::US9902719, Example 27

SMILES Fc1cc(ccc1C#N)-c1nc(cc(=O)n1-c1ccc(cc1)C1CC1)N1CCC2NCCC2C1

InChI Key InChIKey=UFXSIXUFBVKJOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292089   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM292089(4-[4-(1,2,3,3a,4,6,7,7a- octahydropyrrolo[3,2-c]py...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM292089(4-[4-(1,2,3,3a,4,6,7,7a- octahydropyrrolo[3,2-c]py...)
Affinity DataIC50: <100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent