BDBM293978 (2S)-5-(2-(4-((3-(3-(2- Methoxyethoxy)-2- methylphenyl)benzo[b]thiophen- 5-yl)methoxy)phenyl)pent-3- yn-1-yl)-1H-tetrazole::US10106553, Compound 10

SMILES COCCOc1cccc(-c2csc3ccc(COc4ccc(cc4)[C@H](Cc4nnn[nH]4)C#CC)cc23)c1C

InChI Key

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 293978   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM293978((2S)-5-(2-(4-((3-(3-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  54nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM293978((2S)-5-(2-(4-((3-(3-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM293978((2S)-5-(2-(4-((3-(3-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  54nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed