BDBM29410 7-alkoxyisoquinoline, 20

SMILES NCc1ccc(cc1)-c1cc2ccncc2cc1OC1CCNCC1

InChI Key InChIKey=DDEHKSKCGIBOPH-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29410   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Gsk

LigandBDBM29410(7-alkoxyisoquinoline, 20)Copy SMILESCopy InChI

Affinity DataIC50:  126nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Gsk

LigandBDBM29410(7-alkoxyisoquinoline, 20)Copy SMILESCopy InChI

Affinity DataIC50:  6.31E+3nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI