BDBM294927 2-(4,6-Dimethylpyrimidin-2-yl)-5-{[2-fluoro-6-(4-methoxypyrimidin-2-yl)phenyl]carbonyl}octahydropyrrolo[3,4-c]pyrrole::US9586962, Example 483::US9586962, Example 484
SMILES COc1ccnc(n1)-c1cccc(F)c1C(=O)N1CC2CN(CC2C1)c1nc(C)cc(C)n1
InChI Key InChIKey=DVPCTIRPUBYLLP-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 294927
Affinity DataKi: 11nM ΔG°: -10.8kcal/moleT: 2°CAssay Description:Chinese ovary cells (CHO) stably expressing human orexin 1 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco...More data for this Ligand-Target Pair
Affinity DataKi: 230nM ΔG°: -9.05kcal/moleT: 2°CAssay Description:Chinese ovary cells (CHO) stably expressing human orexin 1 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco...More data for this Ligand-Target Pair
Affinity DataKi: 284nM ΔG°: -8.92kcal/moleT: 2°CAssay Description:HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nM ΔG°: -7.66kcal/moleT: 2°CAssay Description:HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...More data for this Ligand-Target Pair