BDBM296887 4-[8-(2,7-diazaspiro[3.5]non-7-yl)-5-(4-methylphenyl)imidazo[1,2-a]pyrazin-6-yl]benzonitrile::US10112950, Example 20

SMILES Cc1ccc(cc1)-c1c(nc(N2CCC3(CNC3)CC2)c2nccn12)-c1ccc(cc1)[N+]#[C-]

InChI Key InChIKey=YCTOLLFEKGNWBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 296887   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM296887(4-[8-(2,7-diazaspiro[3.5]non-7-yl)-5-(4-methylphen...)
Affinity DataIC50: <50nMpH: 7.5Assay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent