BDBM29706 Pyridoimidazolone, 5f

SMILES FC(F)(F)c1ccccc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)cc1

InChI Key InChIKey=XTUOFPOMGIJOIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29706   

TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
The Institute of Cancer Research

LigandPNGBDBM29706(Pyridoimidazolone, 5f)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The biological activities (IC50s) of the compounds were determined against the B-RAF (V600E) mutant enzyme in vitro. GST-MEK1, B-RAF (V600E), and inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed