BDBM299181 N-(2-(5-Fluoroisoindolin-2-yl)pyrimidin-4-yl)-1H-indazol-5-amine::US10125144, Example 9::US11311541, Example 189
SMILES Fc1ccc2CN(Cc2c1)c1nccc(Nc2ccc3[nH]ncc3c2)n1
InChI Key InChIKey=PPRQSCUSEPEPNV-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 299181
Affinity DataIC50: 40nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
Affinity DataIC50: 2.93E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE™ Kinase Assay Kit (Invitrogen catalog number PV3793). Pur...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE™ Kinase Assay Kit (Invitrogen catalog number PV3793). Pur...More data for this Ligand-Target Pair
Affinity DataIC50: 2.93E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair