BDBM29992 2-Cyclohexylcarbonylbenzimidazole, 7c

SMILES CCN1CCN(CC1)c1cc2[nH]c(nc2cc1Cl)C(=O)[C@]1(C)CC[C@@](C)(O)CC1

InChI Key InChIKey=NXSFKUCSWRJBEE-HZCBDIJESA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29992   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Banyu Pharmaceutical

LigandPNGBDBM29992(2-Cyclohexylcarbonylbenzimidazole, 7c)
Affinity DataIC50:  2.00E+4nMpH: 7.4 T: 2°CAssay Description:Binding affinity to the hERG K+ channel was measured by displacement of [35S]-radiolabeled MK499 in membranes derived from HEK 293 cells stably trans...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Pharmaceutical

LigandPNGBDBM29992(2-Cyclohexylcarbonylbenzimidazole, 7c)
Affinity DataIC50:  1.40nM EC50:  1.30nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed