BDBM300805 (3S)-3-[4-[[3-[4-[(4-Hydroxy- 1,1-dioxo-thian-4-yl)methoxy]- 2-methyl-phenyl]benzo[b] thiophen-5-yl]methoxy]phenyl] hex-4-ynoic acid::US10131648, Compound 3::US10195178, Compound 3::US9790198, Compound 3

SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc3scc(-c4ccc(OCC5(O)CCS(=O)(=O)CC5)cc4C)c3c2)cc1

InChI Key InChIKey=NXVSEQSYWJINFK-SANMLTNESA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300805   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300805((3S)-3-[4-[[3-[4-[(4-Hydroxy- 1,1-dioxo-thian-4-yl...)
Affinity DataEC50:  5nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300805((3S)-3-[4-[[3-[4-[(4-Hydroxy- 1,1-dioxo-thian-4-yl...)
Affinity DataEC50:  5nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300805((3S)-3-[4-[[3-[4-[(4-Hydroxy- 1,1-dioxo-thian-4-yl...)
Affinity DataEC50:  5nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent