BDBM30135 alpha-sulfone piperidine hydroxamate, 1a
SMILES CC#CCOc1ccc(cc1)S(=O)(=O)C1(CCNCC1)C(=O)NO
InChI Key InChIKey=PVOQKYVUWAHQSO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 30135
Affinity DataIC50: 4.02E+3nMT: 2°CAssay Description:A continuous assay was used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin), which is quenched by en...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research
Wyeth Research
Affinity DataIC50: 201nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit the cleavage of the substrate by the purified enzyme in a fluorescence-based fluorescence resonanc...More data for this Ligand-Target Pair