BDBM30135 alpha-sulfone piperidine hydroxamate, 1a

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)C1(CCNCC1)C(=O)NO

InChI Key InChIKey=PVOQKYVUWAHQSO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30135   

TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM30135(alpha-sulfone piperidine hydroxamate, 1a)
Affinity DataIC50:  4.02E+3nMT: 2°CAssay Description:A continuous assay was used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin), which is quenched by en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM30135(alpha-sulfone piperidine hydroxamate, 1a)
Affinity DataIC50:  201nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit the cleavage of the substrate by the purified enzyme in a fluorescence-based fluorescence resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed