BDBM304096 (R)-5-(3-chloro-6-(difluoromethyl)-2-fluorophenyl)-2-(3-cyclobutyl-1-((4-(ethoxycarbonyl)phenyl)amino)-1-oxopropan-2-yl)pyridine 1-oxide::US10143681, Example 5

SMILES CCOC(=O)c1ccc(NC(=O)[C@H](CC2CCC2)c2ccc(c[n+]2[O-])-c2c(F)c(Cl)ccc2C(F)F)cc1

InChI Key InChIKey=ZVBRLAVQXBANQB-OAQYLSRUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304096   

TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM304096((R)-5-(3-chloro-6-(difluoromethyl)-2-fluorophenyl)...)
Affinity DataIC50:  166nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent