BDBM3064 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 31::6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(4-methylpiperazin-1-yl)propyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL299194::PD 166285 analog

SMILES CN1CCN(CCCNc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)CC1

InChI Key InChIKey=NZUXTCRYWPXTJA-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 3064   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3064(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 31 | 6-(2,...)
Affinity DataIC50:  2.80E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3064(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 31 | 6-(2,...)
Affinity DataIC50:  380nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3064(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 31 | 6-(2,...)
Affinity DataIC50:  150nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM3064(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 31 | 6-(2,...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibitory concentration of compound against mouse Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM3064(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 31 | 6-(2,...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM3064(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 31 | 6-(2,...)
Affinity DataIC50:  237nMAssay Description:Inhibition of chicken c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM3064(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 31 | 6-(2,...)
Affinity DataIC50:  8.70E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed