BDBM309357 N-((S)-1-((4-((S)-1,2-dihydroxyethyl)-6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)amino)-4-methyl-1-oxopentan-2-yl)picolinamide::US9656959, Example 45

SMILES CC(C)C[C@H](NC(=O)c1ccccn1)C(=O)Nc1cc(cc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)[C@H](O)CO

InChI Key InChIKey=UXSBHEQBJCMEGJ-WUFINQPMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309357   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM309357(N-((S)-1-((4-((S)-1,2-dihydroxyethyl)-6-(4-(4-fluo...)
Affinity DataIC50:  300nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent