BDBM312060 5-{[(1R,2S)-2-Aminocyclohexyl]amino}-N-[1-(2-amino-2-oxoethyl)-3-carbamoyl-1H-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide::US9649308, Example 32

SMILES N[C@H]1CCCC[C@H]1Nc1ccn2ncc(C(=O)Nc3cn(CC(N)=O)nc3C(N)=O)c2n1

InChI Key InChIKey=KRZIEXCMOSOHNS-NWDGAFQWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312060   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM312060(5-{[(1R,2S)-2-Aminocyclohexyl]amino}-N-[1-(2-amino...)
Affinity DataIC50:  3nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent