BDBM312581 2-[4-(1-Aminocyclobutyl)phenyl]-3-phenyl-8-(1H-pyrazol-3-yl)imidazo[1,2-b]-pyridazine-6-carboxylic acid::US9604989, Example 67

SMILES NC1(CCC1)c1ccc(cc1)-c1nc2c(cc(nn2c1-c1ccccc1)C(O)=O)-c1cc[nH]n1

InChI Key InChIKey=XQVPXNJBAWQJKJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312581   

TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM312581(2-[4-(1-Aminocyclobutyl)phenyl]-3-phenyl-8-(1H-pyr...)
Affinity DataIC50:  96nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM312581(2-[4-(1-Aminocyclobutyl)phenyl]-3-phenyl-8-(1H-pyr...)
Affinity DataIC50:  58nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent