BDBM312821 1-[3-cyano-5-[2-[(3R)-3-hy- droxy-1-methyl-2-oxo-pyrroli- din-3-yl]ethynyl]phenyl] pyrazolo[3,4-b]pyridine-3- carboxamide::US9605005, Example 111
SMILES CN1CC[C@@](O)(C#Cc2cc(cc(c2)-n2nc(C(N)=O)c3cccnc23)C#N)C1=O
InChI Key InChIKey=ZOTMWAXVCBVWLO-NRFANRHFSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 312821
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 4.86nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair